![]() ![]() TIMI grade flow 0 represented total occlusion, and TIMI grade flow 3 represented normal epicardial perfusion. Phase 1 studied IV streptokinase and IV tPA (tissue plasminogen activator) and assessed "recanalization of the totally occluded artery 90 minutes after the start of drug infusion." For this study, the TIMI Coronary Grade Flow was established to ensure a uniform and consistent method of recording epicardial perfusion on coronary arteriography. doi: 10.1136/heartjnl-2018-314305.In 1983, the TIMI (Thrombolysis in Myocardial Infarction) study group (Brigham and Women's Hospital, Boston, Massachusetts) chose to conduct a randomized, double-blind, multicenter study to assess the efficacy of intravenous (IV) streptokinase. Incidence and outcomes of unstable angina compared with non-ST-elevation myocardial infarction. Puelacher C, Gugala M, Adamson PD, et al. Should non-ST-elevation myocardial infarction be treated like ST-elevation myocardial infarction with shorter door-to-balloon time? Am J Cardiol. Iantorno M, Shlofmitz E, Rogers T, et al. Epidemiology of cardiovascular disease in China and opportunities for improvement: JACC international. Burden of cardiovascular diseases in China, 1990–2016: findings from the 2016 global burden of disease study. Heart disease and stroke statistics-2019 update: a report from the American heart association. The sequential use of TIMI and GRACE scores provide an easy and promising discriminative tool in predicting outcomes in NSTEMI East Asian patients.īenjamin EJ, Muntner P, Alonso A, et al. GRACE showed better predictive accuracy than TIMI in East Asian NSTEMI patients in both in-hospital and long-term outcomes. Combined use of the two risk scores reserved both the convenience of scoring and the predictive accuracy. 0.68 long-term cardiac mortality: 0.91 vs. GRACE risk scores showed a better predictive ability than TIMI risk scores both for in-hospital and long-term outcomes. Compared to TIMI medium group + GRACE < 140 subgroup, the TIMI medium + GRACE high-risk (≥ 140) subgroup had a significantly higher in-hospital events (39.5% vs. Further subgrouping the TIMI medium group showed that half (53.5%) of the TIMI medium risk population was GRACE high risk (≥ 140). GRACE score grouped most patients (45.7%) into high risk, while TIMI grouped the majority (61.2%) into medium risk. Long-term outcomes were all-cause mortality and cardiac mortality in 4-year follow-up.Ī total of 232 patients were included (female 29.7%, median age 67 years), with a median follow-up of 3.7 years. In-hospital endpoints were defined as the in-hospital composite event, including mortality, re-infarction, heart failure, stroke, cardiac shock, or resuscitation. Patients were scored by TIMI and GRACE scores on hospital admission. This retrospective observational study consecutively collected patients in a large academic hospital between 01/01 and and followed for 4 years. Limited study compared two risk scores, the Thrombolysis in Myocardial Infarction (TIMI) and Global Registry of Acute Coronary Events (GRACE) risk scores in the current East Asian NSTEMI patients. Risk stratification in non-ST segment elevation myocardial infarction (NSTEMI) determines the intervention time.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |